With reference to Celiac Disease, consider the following statements -
- It is an autoimmune disorder where the ingestion of gluten leads to damage of the small intestine's lining.
- The disease can manifest at any stage of life following the introduction of gluten into the diet.
- A complete cure is possible through a combination of immunosuppressive drugs and a short-term gluten-free diet.
Which of the statements given above is/are correct?
Explanation - Celiac Disease is an inherited autoimmune condition where the immune system reacts to gluten, sometimes causing damage to the small intestine. Gluten is a protein found in foods containing wheat, barley, or rye. In celiac disease, eating gluten triggers an immune response to the gluten protein in small intestine. Over time, this reaction can damage small intestine's lining and prevent it from absorbing nutrients. This condition is called malabsorption. The intestinal damage often causes symptoms such as diarrhoea, fatigue, weight loss, bloating, or anaemia. It also can lead to serious complications if it is not managed or treated. In children, malabsorption can affect growth and development in addition to gastrointestinal symptoms. It can develop at any age after people start consuming gluten. It is estimated to affect 1 in 100 people worldwide. There's no definite cure for celiac disease. But for most people, following a strict gluten-free diet can help manage symptoms and help the intestines heal.
Explanation - Celiac Disease is an inherited autoimmune condition where the immune system reacts to gluten, sometimes causing damage to the small intestine. Gluten is a protein found in foods containing wheat, barley, or rye. In celiac disease, eating gluten triggers an immune response to the gluten protein in small intestine. Over time, this reaction can damage small intestine's lining and prevent it from absorbing nutrients. This condition is called malabsorption. The intestinal damage often causes symptoms such as diarrhoea, fatigue, weight loss, bloating, or anaemia. It also can lead to serious complications if it is not managed or treated. In children, malabsorption can affect growth and development in addition to gastrointestinal symptoms. It can develop at any age after people start consuming gluten. It is estimated to affect 1 in 100 people worldwide. There's no definite cure for celiac disease. But for most people, following a strict gluten-free diet can help manage symptoms and help the intestines heal.