Consider the following statements regarding Kikuchi-Fujimoto Disease (KFD) -
- It is a rare inflammatory disorder primarily affecting the lymph nodes in the neck region.
- It predominantly affects individuals above the age of 50.
- It can closely mimic tuberculosis and lymphoma in its clinical presentation.
- Corticosteroids are the first-line treatment for all cases of KFD.
Which of the statements given above are correct?
Explanation - Kikuchi-Fujimoto disease (KFD), also known as histiocytic necrotising lymphadenopathy, is a rare inflammatory disorder of the lymph nodes. It causes swollen, painful lymph nodes that most often develop in neck (cervical lymphadenopathy), along with fever and fatigue. It most often affects people aged 30 and under. It can closely mimic tuberculosis and lymphoma. Causes: The cause of KFD remains unclear, but both viral infections and autoimmune mechanisms have been suggested as potential triggers. Usually, this disease does not cause severe problems and gets better on its own. However, in some people, it can be associated with autoimmune disorders, conditions where the immune system mistakenly attacks the body’s cells and tissues. Treatment — There isn’t a specific cure, but certain medication can help to relieve symptoms, including: NSAIDs (nonsteroidal anti-inflammatory drugs), for fever, pain, and headache. Corticosteroids may be used in severe cases to reduce swelling in lymph nodes.
Explanation - Kikuchi-Fujimoto disease (KFD), also known as histiocytic necrotising lymphadenopathy, is a rare inflammatory disorder of the lymph nodes. It causes swollen, painful lymph nodes that most often develop in neck (cervical lymphadenopathy), along with fever and fatigue. It most often affects people aged 30 and under. It can closely mimic tuberculosis and lymphoma. Causes: The cause of KFD remains unclear, but both viral infections and autoimmune mechanisms have been suggested as potential triggers. Usually, this disease does not cause severe problems and gets better on its own. However, in some people, it can be associated with autoimmune disorders, conditions where the immune system mistakenly attacks the body’s cells and tissues. Treatment — There isn’t a specific cure, but certain medication can help to relieve symptoms, including: NSAIDs (nonsteroidal anti-inflammatory drugs), for fever, pain, and headache. Corticosteroids may be used in severe cases to reduce swelling in lymph nodes.