With reference to Creutzfeldt-Jakob Disease (CJD), consider the following statements:
- It is caused by abnormal forms of proteins called prions that can transmit their incorrect structure to healthy prion proteins.
- The disease primarily affects the respiratory system, with neurological symptoms appearing only in advanced stages.
- Most patients diagnosed with CJD survive for at least five years after the onset of symptoms with appropriate treatment.
- The global incidence of CJD is approximately 1 to 2 cases per million people annually, making it a rare condition.
Which of the statements given above are correct?
Explanation:
Statement 1 is correct. CJD is caused by abnormal forms of proteins called prions. When abnormal prions form, they can transmit their incorrect and damaging form to nearby healthy prion proteins, causing them to change into abnormal prions that clump together in brain tissue.
Statement 2 is incorrect. CJD primarily affects the nervous system, not the respiratory system. The main symptoms are cognitive decline leading to dementia, involuntary muscle jerks (myoclonus), and lack of coordination of movements.
Statement 3 is incorrect. Most people with CJD will die within a year of the symptoms starting, usually from infection, not survive for five years. There is currently no cure for CJD, and treatment aims only to relieve symptoms.
Statement 4 is correct. About 1 to 2 cases of CJD are diagnosed per million people around the world each year, making it a very rare condition that most often affects older adults.
Explanation:
Statement 1 is correct. CJD is caused by abnormal forms of proteins called prions. When abnormal prions form, they can transmit their incorrect and damaging form to nearby healthy prion proteins, causing them to change into abnormal prions that clump together in brain tissue.
Statement 2 is incorrect. CJD primarily affects the nervous system, not the respiratory system. The main symptoms are cognitive decline leading to dementia, involuntary muscle jerks (myoclonus), and lack of coordination of movements.
Statement 3 is incorrect. Most people with CJD will die within a year of the symptoms starting, usually from infection, not survive for five years. There is currently no cure for CJD, and treatment aims only to relieve symptoms.
Statement 4 is correct. About 1 to 2 cases of CJD are diagnosed per million people around the world each year, making it a very rare condition that most often affects older adults.
